Endocrine Cancer

Endocrine cancers are a group of malignancies that originate in the hormone-producing glands of the endocrine system, such as the thyroid, adrenal glands, pancreas, and pituitary gland. These cancers are relatively rare compared to other forms of cancer, but their impact on hormonal balance and metabolic functions can be significant. Because endocrine glands regulate essential body processes—including growth, metabolism, stress response, and reproduction—tumors in these glands may lead to both structural and hormonal complications. Early diagnosis is crucial, as some endocrine cancers grow slowly and present subtle symptoms that may initially be attributed to hormonal imbalances rather than malignancy. Thyroid cancer is the most common type of endocrine cancer, with papillary thyroid cancer representing the majority of cases. Other forms include adrenal cortical carcinoma, neuroendocrine tumors (NETs), medullary thyroid carcinoma, and cancers of the parathyroid or pituitary glands. The causes of endocrine cancers can vary and may include genetic syndromes such as MEN1 and MEN2 (Multiple Endocrine Neoplasia), inherited gene mutations, radiation exposure, and chronic hormonal disturbances. Symptoms often differ depending on the gland involved, but may include unexplained weight changes, fatigue, abnormal hormone levels, blood pressure fluctuations, or palpable glandular swelling.

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